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Brian K Kaspar Selected Research

Peroxisome Proliferator-Activated Receptors (PPAR)

12/2015Translational profiling identifies a cascade of damage initiated in motor neurons and spreading to glia in mutant SOD1-mediated ALS.

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Brian K Kaspar Research Topics

Disease

9Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease)
09/2018 - 05/2005
6Spinal Muscular Atrophy (Progressive Muscular Atrophy)
01/2019 - 01/2009
5Neurodegenerative Diseases (Neurodegenerative Disease)
01/2020 - 01/2009
4Disease Progression
11/2019 - 08/2003
3Duchenne Muscular Dystrophy (Muscular Dystrophy, Becker)
01/2017 - 10/2012
3Paralysis (Palsy)
03/2015 - 05/2005
2Machado-Joseph Disease (Spinocerebellar Ataxia Type 3)
11/2019 - 02/2015
2Neuroinflammatory Diseases
11/2019 - 02/2015
2Inflammation (Inflammations)
12/2015 - 03/2014
2Spinal Cord Injuries (Spinal Cord Injury)
01/2015 - 10/2011
2Rett Syndrome (Rett's Disorder)
08/2013 - 06/2011
2Nervous System Diseases (Neurological Disorders)
08/2013 - 11/2012
1Hypertrophy
01/2021
1Atrophy
11/2019
1Motor Neuron Disease (Primary Lateral Sclerosis)
11/2017
1Inclusion Body Myositis
01/2017
1Spinal muscular atrophy with respiratory distress 1
03/2015
1Muscle Weakness
03/2015
1Demyelinating Diseases (Demyelinating Disease)
01/2015
1Amyloid Plaque
02/2014
1Alzheimer Disease (Alzheimer's Disease)
02/2014
1Limb-Girdle Muscular Dystrophies (Limb-Girdle Muscular Dystrophy)
10/2012
1Autism Spectrum Disorder
06/2011
1Peripheral Nervous System Diseases (PNS Diseases)
08/2010
1Muscular Diseases (Myopathy)
11/2009
1Infections
02/2006
1Hypersensitivity (Allergy)
06/2003
1Pain (Aches)
06/2003

Drug/Important Bio-Agent (IBA)

6Proteins (Proteins, Gene)FDA Link
11/2019 - 05/2005
3FollistatinIBA
01/2021 - 01/2015
3Superoxide Dismutase-1IBA
09/2018 - 12/2013
3Transcription Factors (Transcription Factor)IBA
12/2015 - 06/2011
2Small Interfering RNA (siRNA)IBA
01/2020 - 05/2005
2Superoxide DismutaseIBA
04/2015 - 05/2005
2Biomarkers (Surrogate Marker)IBA
03/2015 - 01/2014
2Nerve Growth Factors (Neurotrophins)IBA
02/2015 - 08/2010
2Methyl-CpG-Binding Protein 2IBA
08/2013 - 06/2011
2Pharmaceutical PreparationsIBA
11/2012 - 05/2005
2Insulin (Novolin)FDA Link
06/2008 - 05/2005
1MyostatinIBA
01/2021
1Ataxin-3IBA
11/2019
1Glutamine (L-Glutamine)FDA Link
11/2019
1Messenger RNA (mRNA)IBA
11/2019
1Ibuprofen (Motrin)FDA LinkGeneric
11/2019
1ZolgensmaIBA
01/2019
1Protein Isoforms (Isoforms)IBA
01/2017
1Liver X ReceptorsIBA
12/2015
1Peroxisome Proliferator-Activated Receptors (PPAR)IBA
12/2015
1Neuroprotective AgentsIBA
02/2015
1Dihydrotachysterol (AT 10)IBA
01/2015
1DystrophinIBA
01/2015
1NF-kappa B (NF-kB)IBA
03/2014
1Peptides (Polypeptides)IBA
02/2014
1SDPM1 peptideIBA
02/2014
1Amyloid (Amyloid Fibrils)IBA
02/2014
1Creatine Kinase (Creatine Phosphokinase)IBA
10/2012
1MorpholinosIBA
10/2012
1Sarcoglycans (beta Sarcoglycan)IBA
10/2012
1CorticosteroneIBA
12/2011
1GlucocorticoidsIBA
12/2011
1Transforming Growth Factors (Transforming Growth Factor)IBA
10/2011
1Insulin-Like Growth Factor I (IGF-1)IBA
06/2008
1Neutralizing AntibodiesIBA
02/2006
1Insulin-Like PeptidesIBA
08/2003
1Formaldehyde (Formol)FDA Link
06/2003
1NMDA receptor A1IBA
06/2003
1Cre recombinaseIBA
06/2003
1N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA
06/2003
1N-Methylaspartate (NMDA)IBA
06/2003

Therapy/Procedure

14Therapeutics
11/2019 - 05/2005
2Intramuscular Injections
01/2017 - 05/2005
2Transplantation
02/2015 - 03/2013
1Artificial Respiration (Mechanical Ventilation)
11/2017